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Methyldopa

Methyldopa is white or off-white crystalline powder; odorless. It is slightly soluble in water, slightly soluble in ethanol, very slightly soluble in ether.

CAS No.: 550-30-6

UN NO.: N/A

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Application:

Methyldopa is a prodrug that can pass through the blood-brain barrier. When it enters the central nervous system, it is metabolized into norepinephrine similar to norepinephrine under the action of aromatic amino acid decarboxylase and dopamine-β-hydroxylase. The pseudotransmitter alpha-methylnorepinephrine, which interacts with central postsynaptic membrane receptors, inhibits the egress of sympathetic nerve impulses, resulting in a drop in blood pressure.

Indications: Treatment of hypertension, more suitable for renal hypertension and pregnancy-induced hypertension.

Packing:

25kg/drum

Specification

USP, EP